It was with slight guilt that when I first saw a picture of
the Ebola virus under a microscope that I thought, “It’s quite pretty!” The viruses Ebola and Marburg together make
up the family Filoviridae, taken from the Latin "filum", meaning
thread-like, based on their string-like structure. The colourful illumination they use to display it makes the virus appear deceptively attractive – the reality is quite the opposite. It is not just the high death rate that makes
people afraid of Ebola – it’s what it does to you in the mean time.
Ebola Virus Disease used to be known as Ebola Haemorrhagic
Fever. Haemor-what, I ask? This basically means it is one of a group of
diseases characterised by fever accompanied by haemorrhage – that is, escape of
blood from spontaneously ruptured blood vessels. Lassa Fever and Yellow Fever also fall into
this category, and are among the range of infectious diseases that Ebola may be
easily mistaken for. Here’s how it goes.
The first stage seems mundane – sufferers experience
flu-like symptoms such as a sudden fever, profound weakness, muscle pain,
headaches and a sore throat.
After 4-7 days, the symptoms develop, and a patient may
experience vomiting, diarrhoea, low blood pressure and anaemia. You can’t see it yet, but these are clues
that the bleeding has started.
Not everyone will make it as far as the final, most gruesome
stage. Some recover, some die before the
bleeding becomes evident beyond some bruising or bleeding from the gums. After 7-10 days, Ebola has been causing blood
vessels to rupture and has prevented coagulation (clotting), so that there is
internal and external bleeding. People
bleed from the eyes, ears and nose. They
may vomit, cough up or excrete blood.
Bleeding under the skin causes a rash all over the body (similar to the
non-blanching rash shown in severe meningitis).
The kidneys are often the first to give up. In the end, at this stage, the bleeding and infection
cause low blood pressure leading to multi-organ failure. That is what will bring their suffering to an
end.
For better or worse, the disease usually takes about two
weeks to run its course. Not so pretty
now.
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